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Spotting Between Periods: Small vaginal bleeding or spotting may happen when the body is getting used to receiving new hormone levels from Semaglutide treatment and is thus the reason for the mid-cycle bleeding

One study reported a composite outcome of mortality and hospitalisation for heart failure ( n =131,196) and found a reduced risk with combination therapy (HR 0.77 [95% CI 0.69, 0.86]) [26]

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